Million people worldwide suffer articular cartilage defects, the causes are caused by diverse. This leads to a variety of aches and pains, because the cartilage is responsible for a smooth sliding motion. In the intact state, it can absorb impact forces that correspond to seven times the body weight. Unfortunately, the hyaline articular cartilage in adults is very limited regeneration. This means that most of the defects by itself does not heal, but some inevitably osteoarthritis are moving to.
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| Healthy cartilage | Knee cartilage damage stages 2-4 |
| The chondrocyte transplantation is currently the world's only process that allows the reconstruction of the original articular surface. It was the 90's by a Swedish team of researchers beginning. It was the knee joint cells were injected in the open surgery technique, which to be transplanting a bone area was then covered with skin flaps, among the cultured. The disadvantages of open surgery such as large scar formation, increased infection and Verklebungsrisiko led to the development of the method towards a purely arthroscopic minimally invasive cartilage transplantation . | |
| Inclusion of spheroids grown - from autologous cartilage cells, each with 82,000 cells per ball |
